If you have a Supermicro H8DA8 motherboard with the latest 5/22/06 BIOS heed this warning. If you have the on board SCSI controller turned on and you turn both serial ports off in the BIOS config your machine will hang on the next boot. The hang will be a blank screen after POST with a blinking cursor in the upper left hand corner of the screen. Supermicro has acknowledged this problem through my correspondence with them. They said it's a problem with the Adaptec controller on the board. The only way to fix it is to leave the serial ports turned on.
If you do turn them off and get the blank screen your will not be able to get back into the bios. To remedy this you will need to disable the SCSI chip by jumping it off on the motherboard. The pin for that is JPA1. Then boot and go into the BIOS and turn the serial ports back on. After that its up to you to jump the SCSI chip back on if you like.